Born in 1975 into a family of musicians in Irkutsk, Siberia, Denis Matsuev began piano studies at the age of four and made his debut when he was nine.
In 1991 he moved to Moscow to study and soon became a laureate of the International Charity Foundation "New Names" program. Through his association with the Foundation, he was afforded the opportunity to perform in more than 400 cities in Russia and 32 countries abroad.
A graduate of the Moscow Conservatory, Mr. Matsuev is a laureate of the International Piano Competition in Johannesburg, South Africa (1994 Grand Prix), laureate of the 1998 International Piano Competition in Paris, and first prize winner of the 1998 International Tchaikovsky Competition in Moscow.
At the 1995-96 Andrew Lloyd Webber Festival in London, Mr. Matsuev was the first classical musician to give recitals performing jazz arrangements and improvising Webber‘s opera themes.
Mr. Matsuev has appeared with Russia‘s leading orchestras, including the State Academic Symphony Orchestra, Moscow Philharmonic and Russia‘s National Symphony. He also has performed with the Tokyo National Symphony Orchestra and the Bucharest National Symphony Orchestra. During 2000 he toured 10 U.S. cities with the Russian National Orchestra and 25 U.S. cities with the Bolshoi Symphony Orchestra.

Since his triumph in the 1998 at the 11th International Tchaikovsky Competition, Denis Matsuev has become a virtuoso in the grandest of Russian pianistic tradition and has quickly established himself as one of the most prominent pianists of his generation.

Mr. Matsuev performs with the world's best known orchestras, such as the New York Philharmonic, Chicago Symphony Orchestra, Philadelphia Orchestra, Los Angeles Philharmonic Orchestra, Pittsburg Symphony Orchestra, Berlin Philharmonic Orchestra, London Symphony, London Philharmonic, Royal Philharmonic Orchestra, Royal Concertgebouw Orchestra, Leipzig Gewandhaus Orchestra, Bavarian Radio Symphony Orchestra, National Symphony Orchestra, WDR of Cologne, BBC Symphony, “Philharmonia” Orchestra of London, Verbier and Budapest Festival Orchestras, Filarmonica della Scala, Maggio Musicale Fiorentino, Accademia Nazionale di Santa Cecilia, Orchestre National de France, Orchestre de Paris, Orchestre Philharmonique de Radio France, NHK Symphony, the Rotterdam Philharmonic, Israel Philharmonic Orchestra as well as the European Chamber Orchestra. He is continually re-engaged with the legendary Russian orchestras such as the St. Petersburg Philharmonic, the Mariinsky Orchestra and the Russian National Orchestra.

Denis gives recitals in the USA in Boston, Washington and New York in Carnegie Hall (Keyboard Virtuosos series), in London in Royal Festival Hall (International Piano series), Madrid in Auditorio Nacional de Musica, Amsterdam in Concertgebouw (Master Pianists series) and Moscow (the Great Hall of Moscow Conservatory).

Denis Matsuev regularly appears with the most distinguished conductors on a stage today, including Valery Gergiev, Yuri Temirkanov, Mariss Jansons, Zubin Mehta, Kurt Masur, Paavo Jarvi, Antonio Pappano, Charles Dutoit, Alain Gilbert, Leonard Slatkin, Myung-Whun Chung, Semyon Bychkov, Iván Fischer, Adam Fisher, Gianandrea Noseda, Jukka-Pekka Saraste, James Conlon, Vladimir Spivakov, Mikhail Pletnev, Vladimir Fedoseyev, Yury Bashmet and others.

Mr. Matsuev is a frequent guest of world famous music festivals such as Verbier Festival and Lucerne Music Festival in Switzerland, BBC Proms and Edinburgh International Festival in Great Britain, Schleswig-Holstein, Rheingau, Festspielhaus Baden-Baden in Germany, Les Chorégies d’Orange and Festival de la Rogue d’Anthéron in France, Ravinia and the Hollywood Bowl in the U.S., Chopin Festival in Poland, Maggio Musicale Fiorentino and Mito Festival in Italy, Montreux Festival in Switzerland, Enescu Festival in Romania, Baltic Sea Festival in Sweden and Stars of the White Nights Festival in Russia.

For 11 consecutive years Denis Matsuev has his original series at The Great Hall of Moscow Conservatory “Denis Matsuev invites…”. Many famous orchestras, prominent conductors, outstanding soloists have taken part in it.

In 2010, in Avery Fisher Hall, the New York Philharmonic gave the orchestra’s 15,000th concert – a number unmatched by any other orchestra. Denis Matsuev was a leading soloist in this unprecedented milestone concert, which was conducted by Maestro Valery Gergiev, and was praised highly by music critics.

For many years Denis Matsuev has led numerous musical festivals and educational projects which have added to his role as a prominent public figure. Since 2004 he has organized “Stars on Baikal” in Irkutsk, Siberia (in 2009 he was awarded the title of Honorary Citizen of Irkutsk), and since 2005 he has been the artistic director of the music festival “Crescendo” (a series of events held in international cities such as Moscow, St. Petersburg, Yekaterinburg, Tel Aviv, Kaliningrad, Paris and New York). In 2010 he became the artistic director of Annecy Music Festival in Annecy, France, with the goal to bring together Russian and French music cultures. In 2012 Denis Matsuev became the artistic director of I International “Astana Piano Passion” Festival and Competition as well as the artistic director of International Festival and Competition “Sberbank DEBUT” in Kiev in 2013. In 2016 Denis Matsuev as the artistic director of the Competition and chairman of the Organizing Committee started a new competition for young pianists in Moscow - Grand Piano Competition. Additionally, Mr. Matsuev is the president of the charitable Russian foundation “New Names” that discovers and supports talented children and helps to develop music education in regions of his native Russia. More than 10000 children received monetary grants and/or opportunity to perform at the professional stage.

In 2007, RCA Red Seal released “Unknown Rachmaninoff” featuring Mr. Matsuev. The recording has received strong positive reviews praising his execution and creativity. His Carnegie Hall recital in November 2007 was recorded and released in 2009 as an album entitled “Denis Matsuev – Concert at Carnegie Hall.” The New York Times praised this performance writing “…his poetic instincts held fast in tender moments, with trills as thrillingly precise as one might ever hope to hear.”

Mariinsky Label releases include Rachmaninoff Concerto No. 3, Shostakovich Concertos No. 1, No. 2 and Schedrin’s Fifth with Valery Gergiev and the Mariinsky Orchestra in the famed Mariinsky Concert Hall. Among many awards granted is the Five Star rating of BBC Music Magazine. Norman Lebrecht wrote: “Neither is a virtuoso vehicle and, the composer apart, there is no pianist who has stamped these works decisively as his or her own. Denis Matsuev, a Siberian who made his name in Rachmaninoff is perhaps the first to come close”.

In April 2013 Denis Matsuev presented the record (RCA Red Seal) with S. Rachmaninoff’s Piano Concerto No. 2 and Rhapsody in Blue by G. Gershwin, accompanied by the New York Philharmonic under the baton of its music director Alan Gilbert.

In September 2013 the label LSO Live released a new disc with Denis Matsuev and LSO under baton of Valery Gergiev performing Symphonia Concertante by K. Szymanowski.

Gramophone has chosen Denis Matsuev’s recording of Tchaikovsky Concerti Nos. 1 & 2 as their recording of the month in April 2014.

“Matsuev’s Tchaikovsky No 1 is thrilling, the work’s drama excitingly to the fore – a new ‘personal benchmark’, says Jeremy Nicholas. That’s for you to decide, of course, but do hear it.” Gramophone (UK)

For many years Denis Matsuev has collaborated with the Sergei Rachmaninov Foundation, established by Alexander Rachmaninov, the grandson of the composer. Mr. Matsuev was chosen by the Foundation to perform and record Rachmaninov’s unknown pieces on the composer's own piano at the Rachmaninov house “Villa Senar” in Lucerne. Later, he became the artistic director of the Foundation. In 2013 – Rachmaninov’s 140th anniversary year – the Foundation presented series of concerts in the most prestigious concert halls throughout Russia and Europe.

Denis Matsuev is a laureate of prestigious “Shostakovich’s Prize” in Music as well as the State Prize of Russian Federation in Literature and Arts. He also is a “People’s Artist of Russia.” Denis Matsuev was named Honorary Professor of Moscow State University. He is a member of The Presidential Council for Culture and Arts, Honored Artist of Russia and he recently became the head of The Public Council under The Ministry of Culture of the Russian Federation.

In February 2014 Denis Matsuev was awarded the honour of performing at the official Closing Ceremony of the XXII Winter Olympic games in Sochi.

In April 2014 UNESCO designated Denis Matsuev as a UNESCO Goodwill Ambassador.